PROM1 and cancer: Regarding the role of garlic and its main constituents on cancer stem cells, a hydroalcoholic garlic extract (obtained using fresh cloves treated with 40% ethanol), which contains diallyl sulfide, diallyl disulfide, dipropenyl disulfide, and allyl methyl trisulfide (identified using GC-MS analysis), reduced the growth of CD133+ MCF-7 breast cancer stem cells and inhibited the epithelial to mesenchymal transition, induced by hypoxia [248].