VIM and triple-negative breast carcinoma: Another compound, 2-hydroxycinnamaldehyde, showed promising results on triple negative breast cancer cell lines through (i) the inhibition of epithelial to mesenchymal transition, (ii) the down-regulation of vimentin, Snail transcriptional factor, and EGF, (iii) the up-regulation of GSK-3β nuclear level, and iv) the down-regulation of transcriptional factors Id-1 and SP1, involved in breast cancer invasion [277].