A walnut extract, rich in phenolic compounds (catechin—137.5 mg/100 g, chlorogenic acid—13.6 mg/100 g, ellagic acid—12.6 mg/100 g, and gallic acid—10 mg/100 g) showed promising results on colorectal cancer stem cells by suppressing stemness markers (Notch 1, DLK1, CD44, CD133) and the down-regulation of Wnt/β-catenin signaling pathway [16]. This evidence concerns the gene PROM1 and colorectal cancer.