Observed symptoms of this disease include the following: common ketoacidosis and hypoglycemia, severe hyperglycemia, normal or increased peripheral insulin sensitivity, low glucose levels, normal or high levels of glucagon and pancreatic peptide (PP), normal or low levels of glucose-dependent insulinotrophic polypeptide (GIP) and normal levels of glucagon-like peptide 1 (GLP1). The gene discussed is GLP1R; the disease is Hypoglycemia.