In an assessment of serum levels of several interleukins (IL), like IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-17, tumor necrosis factor-α (TNF-α), interferon-α (IFN-α), and interferon-γ (IFN-γ) in patients suspected of having CAD who underwent coronary angiography, IL-8 levels did not differ significantly between those with no, mild, or severe CAD. This evidence concerns the gene TNF and coronary artery disorder.