rs675388 of KCNJ1 was associated with ex-smoker status (p-value = 0.004), B-blocker (p-value = 0.002), angiotensin-converting enzyme inhibitor (ACEi) (p-value = 0.031), other HTN medications from other classes (p-value = 0.04), immune-suppressive/allergies (p-value = 0.033), ischemic heart disease (IHD) (p-value = 0.049), and left ventricular hypertrophy (LVH) on ECG (p-value = 0.025). This evidence concerns the gene ACE and hypertensive disorder.