Compared to 4 hpi, BMDMs at 36 hpi exhibited enhanced enrichment in genes related to pathways seen in diseases (such as Amoebiasis, alcoholic liver disease, and COVID-19), receptor signaling (such as RIG-I-like receptor signaling pathway and C-type lectin receptor signaling pathway), IL-17 signaling pathway, and the positive regulation of nitric oxide biosynthetic pathway (Figure 4E). The gene discussed is IL17A; the disease is alcoholic liver diseases.