Leber Hereditary Optic Neuropathy (LHON) mostly occurs as a result of one of the three-point mutations in mtDNA located at nucleotides 11,778, 14,484 and 3460, all affecting the NADH dehydrogenase (ND) subunits of complex I of the electron transport system (ETS) [1,2]. This evidence concerns the gene ENSG00000251605 and Leber hereditary optic neuropathy.