TMEM109 and renal carcinoma: Additionally, 10 SASP-encoding genes, including ACADM, ATP6V0A1, CKM, FUCA1, GALE, IDH2, RHOC, TMEM109, TUBA4B, and TUBB2A, were significantly downregulated (Log2 ratio < −1.15, p < 0.05) in renal cancer.