TP53 and complete blood cell count: The results showed an increased risk of CBC in women carrying protein-truncating variants and rare missense variants in BRCA1 (HR 2.88), BRCA2 (HR 2.31), and TP53 (HR 8.29), and protein-truncating variants in CHEK2 (HR 2.25) and PALB2 (HR 2.67) [153].