DKK1 and lung adenocarcinoma: The results showed that, among the 45 TSPX-mediated DEGs involved in pathways related to cell proliferation and cell viability in A549 and SK-MES-1 cells (Figure 4C), nine genes showed the same expression pattern in clinical samples of lung adenocarcinomas in relation to TSPX expression level, i.e., AREG, BIRC3, CXCL5, DKK1, EREG, FOSL1, MYC, PLAU, and CACNA2D2 (Figure 5A).