KIT Proto-Oncogene, Receptor Tyrosine Kinase (KIT, also known as C-KIT or CD177) is involved in crucial biological processes, such as cell proliferation, differentiation, and survival, and has been implicated in various malignancies, e.g., gastrointestinal stromal tumors, breast cancer, thyroid cancer, and colorectal cancer; thus, its potential targeting for therapeutic reasons is attracting clinical and research interest [82,83]. The gene discussed is CD177; the disease is gastrointestinal stromal tumor.