DUX4 and facioscapulohumeral muscular dystrophy: Along this line, the proteomics-based study of primary cells cultured from skeletal muscle biopsies collected from patients is a promising analytical approach to decipher pathophysiologies of inherited muscle diseases or to unveil liquid biomarkers indicative of the associated myopathology, as exemplified for DUX4 targets in the context of Facioscapulohumeral muscular dystrophy (FSHD) [10,11].