Our study aimed to determine the inhibitory effects of morin on the gene expression of NLRP3, as well as pro-inflammatory cytokines (IL-6, IL-1β, and IL-18), in LPS+ATP-stimulated NSCLC cell lines, specifically A549 and H1299 cells, using RT-qPCR analysis to measure mRNA expression. The gene discussed is NLRP3; the disease is non-small cell lung carcinoma.