Enrichment analyses of these targets resulted in 123 reactome pathways overrepresented (FDR < 0.05; Supplementary Table S6); the top 20 are depicted in Figure 6B. Many of these pathways are highly related to the immune system, including “HSA-1280215: Cytokine Signaling in Immune System”, “HSA-9006936: Signaling by TGFB family members”, “HSA-983705: Signaling by the B Cell Receptor (BCR)”, or “HSA-5663205: Infectious Disease” (Figure 6B; Supplementary Table S6). The gene discussed is TGFB1; the disease is infectious disease.