Additionally, myricetin showed inhibitory effects on MMP-2 enzyme activity in various human CRC cell lines including COLO 320HSR, COLO 320DM, HT-29, and COLO 205-X, with IC50 values of 11.18, 11.56, 13.25, and 23.51 μmol/L, respectively. Here, MMP2 is linked to colorectal carcinoma.