Through spatial transcriptomics analyses of multiple hepatoblastoma-like malignancy samples, Fang J. et al. [23] found that the expression of Dlk1, Epcam, and Gpc3, the embryonal hepatoblastoma stem cell markers, exhibited intertumoral heterogeneity, and the differentiation degree of tumors varied among different patients. Here, EPCAM is linked to hepatoblastoma.