Inhibitory activity towards HDAC enzymes in human hepatoma and colon cancer cell lines [65]Promotion of H3 histone hyperacetylation in hepatoma and colon tumor cells [65]Binding to DNMT1 in colorectal cancer cell lines, thus downregulating DACT2 methylation and inhibiting Wnt/β-catenin pathway [90]Regulation of miR-340 expression in lung tumor [7,66]. The gene discussed is HDAC9; the disease is hepatocellular carcinoma.