Zerr et al. [29] conducted a comprehensive comparative analysis of plasma NF-L and t-tau levels in healthy controls and patients with a diverse spectrum of neurological disorders, including non-neurodegenerative neurological diseases (both with and without dementia syndrome), AD, CJD, Lewy body disease (LBD), frontotemporal lobular dementia, and vascular dementia. This evidence concerns the gene NEFL and nervous system disorder.