STRING analysis of the 11 dysregulated proteins from the whole PCOS cohort and the BMI-matched PCOS cohort indicate that, although these proteins have limited direct interactions, they are well connected through their immediate binding partners, such as interleukin 10 (IL10), C-C motif chemokine ligand 3 (CCL3) and interleukin 1 alpha (IL1A), which are reported as active members in cytokine regulation, cytokine–cytokine interaction, inflammatory responses and, for example, angiopoietin 2 (ANGPT2), angiopoietin 4 (ANGPT4), and angiogenin (ANG) that have specific roles in vascular function. This evidence concerns the gene IL1A and polycystic ovary syndrome.