AKT1 and cancer: Different signaling pathways, such as phosphatidylinositol-3 kinase/protein kinase B (PI3/Akt), the mammalian target of rapamycin (mTOR), and Wnt/β-catenin are intricately linked to cancer-related conditions such as altered mitochondrial function, increased production of reactive oxygen species (ROS), and metabolic reprogramming.