IL6 and colitis: In a study involving mice with TNBS-induced colitis, administration of GF ethanol extract for 7 days resulted in reduced Disease Activity Index (DAI) scores, improved intestinal morphology, and decreased expression levels of myeloperoxidase (MPO), nitric oxide (NO), malondialdehyde (MDA), Interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and Interleukin-6 (IL-6) in the colon [18].