High values of Immunoscore index, which assesses the abundance of CD3+ and CD8+ TIL subsets at tumor loci, and Immunosign 21, which assesses the expression of the set of genes associated in particular with T-cells (CD3D, CD3E, CD3G, CD8A, GZMA, GZMB, GZMK, and GZMM) were significantly positively correlated with OS in patients with LBCL treated with axi-cel [60,61]. The gene discussed is CD8A; the disease is neoplasm.