To directly compare the potency of the CEA TCB across the different cancer spheroids and healthy organoid lines, we analyzed the specific lysis after 72 h in the 3D-RDL assay, quantified by the ATP content, between the rectal and intestinal healthy organoids and the 3D cancer spheroids derived from MKN-45 and DLD-1. Here, CEACAM5 is linked to cancer.