Studies exploring the timeline of transformation in non-EGFR mutant NSCLC are limited, but one study that compared EGFR-mutant to non-EGFR mutant NSCLC noted that non-mutant tumors took longer to transform to SCLC (26 months vs. 16 months for EGFR-mutant) [10]. The gene discussed is EGFR; the disease is small cell lung carcinoma.