Using their T-LUAD and T-SCLC datasets [55], Quintanal-Villalonga et al. found that XPO1 was upregulated in T-SCLC tumors relative to T-LUAD, with similar trends observed in prostate cancer models of NE transformation, suggesting that XPO1 may facilitate NSCLC-to-SCLC transformation [56]. The gene discussed is XPO1; the disease is non-small cell lung carcinoma.