Pearson’s correlation analysis suggested a link between CD31/34 and lncRNA NR2F1-AS1 and further proved that lncRNA NR2F1-AS1 activates IGF-1/IGF-1R/ERK pathways that promotes angiogenesis and metastasis using in vitro and in vivo breast cancer models [70]. Here, IGF1 is linked to breast carcinoma.