STING1 and Thrombocytopenia: In melanoma-bearing mice, the use of STING agonist led to thrombocytopenia and reduction in the total WBC count, which was related to the drop in the number of lymphocytes and monocytes These data indicate that the local administration of the STING agonist led to the systemic change at the cellular level, which is mediated through complex cytokine—cell communication.