Obesity is associated with the presence of prothrombotic factors (e.g., fibrinogen, homocysteine), inflammatory markers (e.g., interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP)), and adipocytokines (e.g., leptin, adiponectin)) [9]. Here, LEP is linked to obesity due to melanocortin 4 receptor deficiency.