Of the bacteria outliers from the bacterial complexes, Aggregatibacter actinomycetemcomitans was investigated by four studies [17,24,27,28] in 82 subjects (80.39% of the total population) of which 52 with periodontitis (63.41%) [24,28] and 30 with MIPP (36.59%) [17,27]. This evidence concerns the gene MINPP1 and periodontitis.