Among the 17 subjects investigated for HSV, 4 subjects were positive (23.53%) (n = 4, 23.53% MIPP) [17] and 13 negative (76.47%) (n = 12, 70.59% MIPP; n = 1, 5.88% periodontitis) [17,26,27]. Here, MINPP1 is linked to periodontitis.