We also measured the protein levels of MYH7, atrial natriuretic peptide (ANP), and brain natriuretic peptide (BNP), which are established biomarkers for cardiac hypertrophy and heart failure, in mouse cardiac tissue and found significant increases in these biomarkers, which were reversed by baicalin treatment (Figure 1F). The gene discussed is NPPB; the disease is cardiac hypertrophy.