There is no doubt that strong survival regulators such as Bcl-2 and Bcl-xL need a tight expression and function regulation, and deficiencies in this control are related to the development of different diseases, namely, different types of cancer [127,128], bone deficiencies [129], asthma complications [130], anemia [131,132,133], and neuronal abnormalities [134,135]. The gene discussed is BCL2L1; the disease is cancer.