APOA1 and scleroderma: Ferraz-Amaro et al. examined 73 SSc patients and 115 controls, and found lower high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and apolipoprotein A-I (Apo A-I) levels and higher lipoprotein (a) (Lp (a)), triglyceride, Apo B/A-I ratio and atherogeneity index (total cholesterol/HDL-C) in the scleroderma group [19].