TARDBP and injury: The Western blot analyses, performed with specific anti-phospho(409/410)-TDP-43 antibody, detected a significant decrease in phosphorylated TDP-35 fragment (P-TDP-35) expression on day 1 after single brain trauma (Figure 2F) [F(2,7) = 8.933; p = 0.012] compared to the animals of the control group (p = 0.004) and animals sacrificed 3 days after moderate LFPI (p = 0.034).