Johari et al. demonstrated (in a randomized controlled trial with per-protocol and intention-to-treat analysis on 43 individuals with NAFLD) a positive effect of applied temporary caloric restriction on ALT levels and hepatic steatosis assessed using magnetic resonance imaging [77]—similar results in their study using liver elastography were obtained by the Australian group Feehan et al. (on a group of 34 patients during a 12-week trial) [78]. This evidence concerns the gene GPT and fatty liver disease.