INS and Insulin resistance: Polyunsaturated fatty acids are no less important, especially maintaining an appropriate ratio of n-6 acids to n-3 acids—as it has been previously demonstrated (on animal models) that an appropriate meal composition in this regard (and especially an increased supply of α-linolenic acid relative to n-6 acids) improves peripheral insulin sensitivity and lowers cholesterol and triglyceride concentrations in cases of fructose-dependent insulin resistance burden [34].