Regular aerobic exercise such as brisk walking, Nordic walking, etc. has a beneficial effect on the remission of hepatic steatosis mainly due to the regulation of fatty acid oxidation (using adiponectin and AMP kinase), leptin, intrahepatic SREBP-1c levels and the action of antioxidant enzymes [123,124]. The gene discussed is ADIPOQ; the disease is Hepatic steatosis.