Human immunodeficiency virus type I enhancer binding protein 2 (HIVEP2) encodes atranscription factor with zinc finger domains that regulates many neurodevelopmental pathways and it has been identified in many neurodevelopmental disorders, intellectual disability, behavioral symptoms, hypotonia, autism spectrum disorders, and microcephaly [34,35,36,37]. The gene discussed is HIVEP2; the disease is Intellectual disability.