TRIM5 and prostate adenocarcinoma: MARCO, LAYN, and IL10RB were linked to reduced PRAD risk, while C1QA, TXNDC15, IGFBP3, TNFRSF10C, TRIM5, JAM3, RNF43, PPP1R14A, SPINT2, and LGALS4 were associated with increased risk (Figure 2, Table S2).