The deCODE database analysis identified PLXND1 and TNFSF14 as genes linked to a reduced risk of PRAD (Figure 3, Table S5), while NEGR1, REG4, ECM1, GNMT, POR, MTHFD1, and GSTZ1 were associated with increased PRAD risk. This evidence concerns the gene PLXND1 and prostate adenocarcinoma.