“Very-low” quality applied to HC, WC, high-density lipoprotein cholesterol (HDL-C), Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), FSH, LH, DHEAS, free androgen index (FAI), high-sensitivity C-reactive protein (hs-CRP), nitric oxide (NO), and total antioxidant capacity (TAC). The gene discussed is CRP; the disease is Insulin resistance.