SPP1 and renal cell carcinoma: Cells from renal cell carcinoma (RCC) tissue in the dataset GSE167573 [38] showed tumorous samples to have multiple exonic regions in several genes, among them SPP1 or ‘ENSG00000118785’ with five exons (Figure 5C), S100A4 with two exons (Figure 5D) and CXCL12 with five exons (Figure 5E).