In the breast cancer study GSE213474 [28], the second set of MCF7 cell samples, which were supplemented with heat-inactivated FBS (HD) along with estradiol (E2), showed three exonic regions (E017, E018 and E019) of CXCL12 or ‘ENSG00000107562’, to differ significantly with longer time under treatment using IFN-γ stimulation (Figure 5A). This evidence concerns the gene CXCL12 and breast cancer.