The observed decrease in the viability of 12Z epithelial cells under the influence of 0.05 nM PNX-14 can be explained by the cytotoxic effect of endometriosis-related PNX-14 concentration and the increased—after 72 h—mean by activation of adaptive mechanisms, including an increase in migratory capacity, which is also related to the observed negative correlation between CDH1 and THBS2 expression and XTT results. This evidence concerns the gene CDH1 and endometriosis.