NF1 and Global developmental delay: While half of patients (50%, 2/4) exhibited NF1-specific intracranial findings, no other striking clinical features like neurofibroma/plexiform neurofibroma (0%, 0/4), skeletal involvement (0%, 0/4), pseudarthrosis (0%, 0/4), optic glioma (0%, 0/4), or Lisch nodule (0%, 0/4) were observed, except the presence of one case of cognitive/learning disabilities (25%, 1/4) and one case of motor developmental delay (25%, 1/4).