VIM and glioblastoma: Pathenolide, lactucopicrin, cynaropicrin, dyhydroartemisinin, and molephantin were found to increase the lipidated form of microtubule-associated protein 1 light chain 3 (LC3-II) in glioblastoma cells [22,46,52,72,78], and this process was accompanied by the down-regulation of the autophagic substrate p62 [22,72], extensive cytoplasmic vacuolization [46], and strong rearrangement of the vimentin and α-tubulin cytoskeleton [22].