Interestingly, despite a high anti-PMT activity, alantolactone and dihydroartemisinin were found to inhibit the expression of proneural SOX2 and CD133 in glioblastoma cells [60,78], which may indicate the ability of these compounds to affect only specific compartments of the PMT-associated regulome, which requires further investigation. Here, SOX2 is linked to glioblastoma.