Pronounced p53-inducing activity in glioblastoma cells has been shown for costunolide [51], DMAPT-D6 [57], lactucopicrin [22], and dihydroartemisinin [79], with the latter also increasing the phosphorylation level of p53 [79], a necessary step for the achievement of p53-mediated transcriptional programs [89]. Here, TP53 is linked to glioblastoma.