Analysis with the IPA tool identified 14 enzymes related to tumor invasion (MME, MTHFD1, FLT4, AMFR, FER, PRKCA, ALDOB, AOX1, PSMD1, PRPS1, PRDX2, NDST1, RNASE1, F2) (Figure 8). Here, PRPS1 is linked to neoplasm.