Furthermore, miR-155-5p and miR-24-3p, which have been associated with the regulation of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) signaling, were downregulated after the ablation procedure, suggesting that they could possibly influence the inflammatory processes that take place in the arrhythmogenesis of AF. This evidence concerns the gene NOS3 and atrial fibrillation.