RNF213 and cerebrovascular disorder: Not only that of point mutations, frameshift mutations in RNF213 are also associated with aneurysms (c.1214_1216delGAG and c.11415delC), MMD (c.1587_1589delCGC and c.12343_12345delAAA), and cerebrovascular disease (c.1214_1216delGAG and c.11415delC).