β3-depleted (β3_KO) medulloblastoma cells exhibit lipid hydroperoxide accumulation after radiotherapy, indicating ferroptosis, a regulated cell death process induced by ROS and inhibited by antioxidants such as cysteine, glutathione (GSH), and glutathione peroxidase 4 (GPx4) [44]. Here, GPX4 is linked to medulloblastoma.