The following year, researchers from the same institute studied the effects of the Shengmai formula on diesel exhaust particle-induced atherosclerosis and cardiac dysfunction in a myocardial infarction model, finding that the Shengmai formula effectively treated dyslipidemia, atherosclerosis, myocardial ischemia, and oxidative stress in ApoE−/− mice to varying degrees [274]. The gene discussed is APOE; the disease is myocardial infarction.