GYPA and hypertensive disorder: However, GPA expression was significantly reduced in subpopulations C and D of HTN erythrocytes compared to NTI (x ̄ = 25,116 ± 2697 vs. x ̄ = 45,464 ± 4436; p = 0.0076, and x ̄ = 58,403 ± 7558 vs. x ̄ = 107,057 ± 8807; * p = 0.0041, respectively) (Figure 3B).