GPX1 and type 1 diabetes mellitus: In another study, which included 1385 T1D patients from three different cohorts, the T allele of GPX1 rs3448 was associated with the incidence of renal events (HR 1.81, 95% CI 1.16–2.84, p = 0.008) and ESRD (HR 3.34, 95%CI, 1.69–6.98, p = 0.0004) [33].