IFNG and multiple sclerosis: Similarly, the results of using IFN-γ-induced dendritic cell-derived exosomes for the treatment of multiple sclerosis in vivo showed that exosomes were able to transfer a number of miRNAs, specifically miR-219 and miR-9, to the central nervous system (CNS), resulting in myelination in multiple sclerosis as well as demyelination syndromes [119].