Several TGF-β-responsive genes, including WWP1, CARM1, RASGRP1, THBS1, KCTD5, SGCA, EIF3S6, MCAM, FXR2, MTMR3, SOCS3, SLC2A4RG, MMP2, MMP9, and HSP47, have been previously identified in other cancer cell types such as A549 (lung adenocarcinoma) and HPL1D (lung epithelial cells) [26]. The gene discussed is FXR2; the disease is cancer.