Interestingly, all the diagnostic parameters used showed no discriminative differences in their levels between the three clinical entities, except the WBC (Table 1), which was significantly higher in Se compared to the Pn and Se/Pn, similar to the presepsin and IL-8, but unlike the uPAR, which was significantly higher in the combined Se/Pn infection group than in Pn and Se. The gene discussed is CXCL8; the disease is infection.