ITGA5 and neoplasm: Positive correlations were found between HIF-1α tumor positivity and ITGA5 microenvironment (r = 0.282; p = 0.004); HIF-1α microenvironment and ITGA5 microenvironment (r = 0.637; p < 0.001); HIF-1α microenvironment and LOX microenvironment (r = 0.434; p < 0.001); HIF-1α microenvironment and LOX tumor score (r = 0.300; p = 0.002); HIF-1α microenvironment and LOX tumor score (r = 0.332; p = 0.001); ITGA5 microenvironment and LOX tumor score (r = 0.245; p = 0.014); and ITGA5 microenvironment and LOX tumor outcome (r = 0.230; p = 0.022) (Figure 7).